center for systems

& synthetic biology

an NIGMS national systems biology center


Mothers hand over mitochondria to daughters in budding yeast cell division

November 27, 2012

Cellular content such as the mitochondrial network need to be correctly proportioned between mother and daughter cells during cell division.

Now Center investigators Susanne Rafelski, Hao Li, Wallace Marshall and colleagues examine this process in budding yeast, which divides asymmetrically. Their results indicate that while the mitochondrial network size increases with increasing cell size in the bud, the mitochondria-to-cell size ratio continually decreases in aging mothers over successive generations. You can read the UCSF news article and check out the paper published recently in Science to learn more.