center for systems

& synthetic biology

an NIGMS national systems biology center


When are small effects in biology meaningful?

July 27, 2011

New, more quantitative experimental approaches are enabling the detection of even subtle phenotypic changes.  But in what biological situations are small changes meaningful? In the 10th anniversary special issue of Developmental Cell, Hana El-Samad and Hiten Madhani discuss several examples in biology in which taking a quantitative, systems biology perspective will be critical for a more complete understanding of how cells and organisms function. Read more