center for systems

& synthetic biology

an NIGMS national systems biology center


Center Director Authors 'Cell Signaling' Textbook

July 1, 2014

 In a novel approach to teaching about cell signaling, Center Director Wendell Lim has co-authored an undergraduate-to-graduate level textbook with a unique bottom-up view of cell signaling, focusing on common principles and mechanisms underlying many cell signaling processes.

Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drive all signaling, the book develops a conceptual framework through which students can understand how thousands of diver signaling proteins interact with each other in vast interconnected networks. he book first examines the common currencies of cellular information processing and the core components of the signaling machinery. It then shows how these individual components link together into networks and pathways to perform more sophisticated tasks. Many specific examples are provided throughout to illustrate common principles, and provide a comprehensive overview of major eukaryotic signaling pathways.